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Studies on the minimal effective dose of a water-soluble vitamin K substitute in the prevention of hypoprothrombinemia in the newborn infant

✍ Scribed by Sarah Hooker Hardwicke

Book ID
119452545
Publisher
Elsevier Science
Year
1944
Tongue
English
Weight
649 KB
Volume
24
Category
Article
ISSN
1097-6833

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The effect of oral dose volume on the ab
The effect of oral dose volume on the absorption of a highly and a poorly water soluble drug in the rat
✍ David F. Nickerson; Margaret L. Weaver; Francis L. S. Tse πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 488 KB πŸ‘ 3 views

## Abstract The influence of dose volume on drug absorption following oral administration of a highly and a poorly water soluble drug was examined in male Sprague‐Dawley rats. A constant mass of each ^14^C‐labeled compound was given via gavage in dose volumes of 1, 5, 10, and 20 mL kg^βˆ’1^. Blood le