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Studies on the mechanism of trimethoprim-induced hyperkalemia

✍ Scribed by Eiam-ong, Somchai; Kurtzman, Neil A; Sabatini, Sandra

Book ID
109884400
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
645 KB
Volume
49
Category
Article
ISSN
0085-2538

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The effect of ethambutol on uric acid metabolism was assessed in 14 patients, 8 with gout and 6 with tuberculosis. This antituberculous agent produces hyperuricemia by decreasing the renal clearance of uric acid. Although the exact mechanism responsible for this effect of ethambutol remains undefine