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Studies on the interactions of nogalamycin with duplex DNA

โœ Scribed by R.K. Sinha; Papiya Talapatra; Aruna Mitra; Sandip Mazumder


Book ID
115746687
Publisher
Elsevier Science
Year
1977
Weight
870 KB
Volume
474
Category
Article
ISSN
0005-2787

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The noncovalent binding of the antitumour drugs daunomycin and nogalamycin to duplex DNA has been studied using electrospray ionisation mass spectrometry (ESI-MS). The conditions for the preparation of drug/duplex DNA complexes and for their detection by ESI-MS have been optimised. Ions correspondin