Synthesis of a phosphoramidite of 2โฒ-deo
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Amanda J. Goddard; Victor E. Marquez
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Article
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1988
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Elsevier Science
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French
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A novel phosphoramidite (9) has been synthesized and shown to be an efficient coupling reagent for the synthesis ofoligonucleotide fragments containing the modified base 5,6-dihydro-5-azacytosine. With a model dihydro-5\_azacytosine/thymine dimer (z), oxidation of the dihydrotriazine ring to the aro