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Studies on the control of lactate dehydrogenase activity in mammalian cells

✍ Scribed by Duffy, P.; Sanderson, J.C.

Book ID: 122387008
Publisher: Elsevier Science
Year: 1971
Tongue: English
Weight: 257 KB
Volume: 244
Category: Article
ISSN: 0304-4165
DOI: 10.1016/0304-4165(71)90078-X

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## Abstract In the active site of lactate dehydrogenase important roles are given to aminoacids His195 and Arg171. The coenzyme nicotinamide adenine dinucleotide (NAD) is required in oxidized form (NAD^+^) for the enzymatic oxidation of the substrate __L__‐lactate. Molecular orbital methods CNDO/2,