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Studies on the Basis for the Toxicity of Acrolein Mercapturates

โœ Scribed by Kumar Ramu; Camarie S. Perry; Tamer Ahmed; Gwyn Pakenham; James P. Kehrer


Book ID
112266218
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
219 KB
Volume
140
Category
Article
ISSN
0041-008X

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Forty-eight dogs were separated into four groups of six males and six females. Acrolein (0.1 % aqueous) was administered in gelatin capsules to three of these groups at dosing levels of 0.1, 0.5 and 1.5 mg kg-' day-' based on results of a range-finding study. After 4 weeks, the high dose was increas