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Studies on synthesis and degradation of eicosanoids by rat hepatocytes in primary culture

✍ Scribed by Tran-Thi, T.A.; Gyufko, K.; Henninger, H.; Busse, R.; Decker, K.


Book ID
122943509
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
622 KB
Volume
5
Category
Article
ISSN
0168-8278

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DNA synthesis in primary adult rat hepatocyte cultures was promoted by epidermal growth factor (EGF), arachidonic acid, and prostaglandins E2 and FLa (PGE2 and PGF2J. Growth promotion by EGF was blocked by 0.1 m M indomethacin and 1 m M aspirin, without affecting cell viability. If verapamil was pre