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Studies on retinal microangiopathy and coronary macroangiopathy in rats with streptozotocin-induced diabetes

✍ Scribed by Waber, Susanne ;Meister, Veronika ;Rossi, G. L. ;Mordasini, R. -C. ;Riesen, W. F.

Publisher: Springer-Verlag
Year: 1981
Weight: 556 KB
Volume: 37
Category: Article
ISSN: 0042-6431
DOI: 10.1007/bf02892551

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## Abstract The pharmacokinetic parameters of 5‐fluorouracil were compared after intravenous administration at a dose of 30 mg/kg to control Sprague–Dawley rats and to rats with diabetes mellitus induced by streptozotocin (DMIS). In DMIS rats, the area under the plasma concentration–time curve from