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Studies on relationships between chemical structure and β-blocking potency of bopindolol and its two metabolites

✍ Scribed by Takafumi Nagatomo; Masaji Ishiguro; Toshio Ohnuki; Kaoru Hattori; Yoshiaki hosohata; Noriyuki Takatsu; Hajime Katayama; Kenichi Watanabe

Book ID: 117175627
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 370 KB
Volume: 62
Category: Article
ISSN: 0024-3205
DOI: 10.1016/s0024-3205(98)00113-1

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## Abstract Zearalenone (ZEN) is a fusarotoxin converted predominantly into α‐zearalenol (α‐Zol) and β‐zearalenol (β‐Zol) by hepatic hydroxysteroid dehydrogenases. The feeding of naturally contaminated grains with ZEN was associated with hyperestrogenic and adverse effects on humans and animals. Th