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Studies on Quinazolines. Part 4. Fused Mesoionic Heterocycles from 3-Amino-2-aryl-4(3H)-quinazolinethiones.

โœ Scribed by A. A. F. Wasfy


Publisher
John Wiley and Sons
Year
2004
Weight
222 KB
Volume
35
Category
Article
ISSN
0931-7597

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๐Ÿ“œ SIMILAR VOLUMES


Studies on quinazolines, part IV: Fused
โœ A. A. F. Wasfy ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 97 KB

## Abstract The 3โ€aminoโ€4(3__H__)โ€quinazolinethiones **__2aโ€“c__** react with phenyl isothiocyanate in DMF, giving N,Nโ€disubstituted thioureas **__3aโ€“c__**. When **__2aโ€“c__** are treated with phenyl isothiocyanate in dry acetonitrile in the presence of triethylamine, the mesoionic compounds **__4aโ€“c

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Reaction of 4H-3.1-benzothiazine-4-lhiones 1 with S-methylisothiosemicarbazide hydroiodide yields bamino-1.3.4-thiadiazoles 2 insteud of the espected 1.2,4-triazolo[3,2-c]quinazolines. Structures of compounds 2 have been established by mcans of '>C-N M R analysis and X-ray crystallography. 3-Arnino-