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Studies on pyridazine compounds, XIX. Mesylation of 5-aminopyrazoles and related compounds

✍ Scribed by Géza Szilágyi; Péter Dvortsák


Publisher
Springer Vienna
Year
1989
Tongue
English
Weight
336 KB
Volume
120
Category
Article
ISSN
0026-9247

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Mesyl guaiacol: a versatile intermediate
✍ Nicolas Bensel; Virginie Pevere; Jean Roger Desmurs; Alain Wagner; Charles Miosk 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 128 KB

An original synthetic pathway for the preparation of 5-substituted guaiacol derivatives is described. This method relies on the deactivation of the phenol group by converting it into the corresponding mesyl ester. Amidomethylation reactions lead to regioselective C C bond formation at the 5-position