✦ LIBER ✦
Studies on peroxidation of arachidonic acid in different liposomes below and above phase transition temperature
✍ Scribed by Giovanna Cervato; Paola Viani; Massimo Masserini; Clara Di Iorio; Benvenuto Cestaro
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 307 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0009-3084
No coin nor oath required. For personal study only.
✦ Synopsis
The mechanism of Fe-induced peroxidation of arachidonic acid (AA) in small unilameilar vesicles (SUV) of dipalmitoyl-phosphatidylehoUne (DPPC) and dipalmitoylphosphatidylethanolamine (DPPE) was studied below and above gel to liquid-crystalline phase transition temperature (T,). In both liposomes the AA peroxidation resulted higher in the temperature range below T, but the extent of malonyldialdehyde (MDA) formation was dramatically lower in DPPE vesicles when compared with corresponding DPPC liposomes. A possible explanation for this is discussed.