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Studies on nuclear estradiol receptors in human mammary carcinomas

✍ Scribed by M. O'Connell; L. McDonnell; M.J. Duffy

Book ID
115824064
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
364 KB
Volume
119
Category
Article
ISSN
0009-8981

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✍ Örian Wrange; Bo Nordenskjöld; Jan-Åke Gustafsson 📂 Article 📅 1978 🏛 Elsevier Science 🌐 English ⚖ 914 KB

Limited trypsin digestion of the estradiol-receptor complex in human mammary cancer cytosol changed the sedimentation coefficient of the complex from 8 to 3-4 S. Gel filtration in high ionic strength on Sephadex columns calibrated with reference proteins showed that, after trypsinization, the Stokes