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Studies on isocyanides and related compounds. A convenient synthesis of 2,3-disubstituted spiroimidazolones

✍ Scribed by Ricardo Bossio; Stefano Marcaccini; Sandro Papaleo; Roberto Pepino


Book ID
112130901
Publisher
Journal of Heterocyclic Chemistry
Year
1994
Tongue
English
Weight
202 KB
Volume
31
Category
Article
ISSN
0022-152X

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Studies on Isocyanides and Related Compo
✍ Bossio, Ricardo ;Marcaccini, Stefano ;Pepino, Roberto πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 238 KB πŸ‘ 1 views

## Abstract The Ugi four‐component condensation between 1,1‐diethoxy‐2‐isocyanoethane (2), cycloketones 1, amine hydrochlorides 4, and potassium thiocyanate (3a) or selenocyanate (3b) affords spiroimidazoles 5, which are cyclized to spiroimidazo[1,5‐__a__]imidazole‐5‐thiones (or selenones) 6.