Studies on diastereoselectivity of the cobalt(I) catalyzed cycloisomerization of substituted ε-acetylenic β-ketoester

✍ Scribed by Paul Cruciani; Corinne Aubert; Max Malacria

• Publisher: Elsevier Science
• Year: 1994
• Tongue: French
• Weight: 229 KB
• Volume: 35
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)73466-6

✦ Synopsis

Abslrucl : Cobalt (I) catalyzed cycloisomerizalion of a E-acelylenic !3'-alkyl p-keloester led lo highly funclionalized methylenecyclopentanes with stereocontrol of two contiguous centers. The lcvcl of diastcreoselectivity is moderate to high (de = 12-92 5%).