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STUDIES ON CYCLOADDITION REACTIONS OF VINYLPHOSPHONATES WITH NITRONES

โœ Scribed by Ye, Yong; Li, Ling-Yun; Tian, Li; Liu, Lun-Zu


Book ID
121691102
Publisher
Taylor and Francis Group
Year
2004
Tongue
English
Weight
118 KB
Volume
179
Category
Article
ISSN
1042-6507

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## Abstract Ferrocenyl nitrones derived from aldehydes or oximes react with electron deficient alkenes to give ferrocenylisoxazolidines. 5โ€Methoxycarbonylisoxazolidines are further transformed to ferrocenylโ€pyrrolidinones by reductive cleavage. The regioโ€ and stereoselectivity of the reactions are

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The intramolecular 1,3-dipolar cycloaddition of ฯ‰-unmolecular cycloaddition, followed by reductive opening of the isoxazolidine ring, produced five-and seven-membered saturated chiral nitrones is described. Starting materials for this reaction are O-protected chiral cyanohydrins, prepared ring compo