Studies on colchicine derivatives. III. Effect on mitotic activity of mouse spermatogonia
โ Scribed by A. Dorothy Bergner
- Publisher
- John Wiley and Sons
- Year
- 1950
- Tongue
- English
- Weight
- 667 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0008-543X
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๐ SIMILAR VOLUMES
OLIC ACID administered to mice 1 hour be-F fore a lethal dose of aminopterin prevents death due to the drug.8 A nonlethal "priming" dose (LD,) of aminopterin abolishes this protective effect.' Simultaneous administration of folinic acid (5-formyl-5,6,7,8-tetrahydropteroylglutamic acid) also protects
Enucleation is the last event in the development of a definitive erythroid line, and extruded nuclei are phagocytosed by macrophages. Both colchicine and cytochalasin have been known to exert a great influence on the enucleation process, but the relationship between enucleation and these agents has