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Studies on binding free energies and the binding mode by docking and MM-PBSA in gp41-ligand complex

โœ Scribed by TAN, J. J.; KONG, R.; CHEN, W. Z.; WANG, C. X.


Book ID
111980949
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
236 KB
Volume
31
Category
Article
ISSN
0892-7022

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We have carried out calculations on the relative free energy of binding of biotin and its S27A and W79A mutants to streptavidin. Consistent with earlier suggestions by Miyamoto and Kollman from free energy component analysis and recent experiments by Stayton and coworkers, the reduction in binding s