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Studies on antifungal agents. 21. Structure of (±)-cis-3-(4-chlorophenyl)-3-(1H-imidazol-1-ylmethyl)-2-methyl-5-(4-chlorophenoxymethyl)isoxazolidine

✍ Scribed by Carroll, P. J. ;Mullen, G. B. ;Georgiev, V. St.


Book ID
114505442
Publisher
International Union of Crystallography
Year
1988
Tongue
English
Weight
350 KB
Volume
44
Category
Article
ISSN
0108-2701

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Studies on Antifungal Agents. Part 25. 1
✍ Grace A. Bennett; Patricia A. Swift; George B. Mullen; Jeffrey T. Mitchell; Stan 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 German ⚖ 468 KB

The synthesis and antifungal activity of a novel series of l-[(3,5-bisaryl-2-methylisoxazolidin-3-yl)methyl]-IH-1,2,4-triazoles 6 and 7 (i.e. 8-19) are discussed. The preparation of 8-19 was straightforward and highlighted by a regiospecific 1,3-dipolar cycloaddition of a -substituted (E)-ketonitron