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Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. IV. Synthesis and biological activity of new 1-substituted derivatives of 4H-s-triazolo[3,4-c]-1,4-benzothiazine and 4,5-dihydro-s-triazolo[3,4-d]-1,5-benzothiazepine

✍ Scribed by V Ambrogi; G Grandolini; L Perioli; GM DeMia; M Ricci; L Tuttobello

Publisher: Elsevier Science
Year: 1991
Tongue: French
Weight: 391 KB
Volume: 26
Category: Article
ISSN: 0223-5234
DOI: 10.1016/0223-5234(91)90011-b

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## Abstract Reaction of 1,5‐benzothiazepines **3**, obtained from chalcones **2** and __o__‐aminobenzenthiol, with the (phenylhydrazino) chloromethylenecarboxylates **4** in the presence of Et~3~N leads to a series of new [1,2,4]triazolo[5,4‐__d__][1,5]benzothiazepine derivatives **5**. Their struc