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Studies on 4-Hydroxycoumarins. XII. 3-Substituted-aminomethyl-4-hydroxycoumarin Derivatives by the Mannich Reaction 1

โœ Scribed by Robertson, Dale N.; Link, Karl Paul


Book ID
117999927
Publisher
American Chemical Society
Year
1953
Tongue
English
Weight
313 KB
Volume
75
Category
Article
ISSN
0002-7863

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## Abstract Starting from 4โ€hydroxycoumarins 4 and 1โ€arylโ€2โ€(dimethylaminomethyl)propโ€2โ€enโ€1โ€ones 2 the title compounds 6 have been synthesized. The reaction is initiated by addition of the Cโ€3 carbon atom of 4โ€hydroxycoumarin to the enone double bond of the Mannich base, subsequent deamination aff