Studies of the stability and reactivity of substituted vinyl titanium triisopropoxides

✍ Scribed by Robert K. Boeckman Jr.; Kenneth J. O'Connor

• Book ID: 104229372
• Publisher: Elsevier Science
• Year: 1989
• Tongue: French
• Weight: 213 KB
• Volume: 30
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)99219-0

✦ Synopsis

The stability and reactivity of vinyl titanium triisopro~xides having a variety of substitution patterns has been explored. These reagents when prepared in Et ,O have proven to be more stable than expected based on prior reports, and they exhibit sufficient reactivity at temperatures where they are stable (-7S"+--600C)

to undergo highly chemoselective addition to a structurally diverse group of aldehydes in fair to excellent yields. However, stereoselectivity obtained upon attempted chelation