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Studies of the responses of basophil and eosinophil leucocytes and mast cells to the nematode Trichostrongylus colubri-formis. I. Observations during the expulsion of first and second infections by guinea-pigs

✍ Scribed by T. L. W. Rothwel

Publisher: John Wiley and Sons
Year: 1975
Tongue: English
Weight: 549 KB
Volume: 116
Category: Article
ISSN: 0022-3417
DOI: 10.1002/path.1711160109

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✦ Synopsis

During expulsion by guniea-pigs of both first and second infections with the intestinal nematode parasite Trichostrongylus colubriformis, increased numbers of basophils and eosinophils were present in the bone marrow and blood. In addition, increased numbers of basophils, mast cells and eosinophils, many possessing reduced numbers of cytoplasmic granules, accumulated at the sites of infection. Blood eosinophil counts, however, did not show significant changes during the early part of a first infection.

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Studies of the responses of basophil and eosinophil leucocytes and mast cells to the nematode Trichostrongylus colubriformis. II. Changes in cell numbers following infection of thymectomised and adoptively or passively immunised guinea-pigs

✍ T. L. W. Rothwell; R. J. Love 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 719 KB

The role of the immune response in the generation of the basophilia and eosinophilia found during expulsion of the intestinal nematode parasite, Trichostrongylus colubriformis, by guinea-pigs was investigated by studying cell numbers in animals whose immune responsiveness had been modified by thymec