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Studies of the metabolizing effect of the S9 liver fraction, hepatic microsomes and microsomal supernatant in the Ames test

✍ Scribed by P. Arni; A. Lüth; E. Deparade; D. Müller

Book ID
113249957
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
71 KB
Volume
74
Category
Article
ISSN
0165-1161

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex