Studies of the meiotic behavior of a translocation t(10;13)(q25;q11) in an oligospermic man
β Scribed by C. Laurent; M. -Cl. Biemont; M. Cognat; B. Dutrillaux
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 205 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
β¦ Synopsis
An new type of translocation, t(10;13)(q25;q11), is observed in a phenotypically normal male who was examined for subfertility. The meiotic behavior of the rearranged chromosomes indicates that crossing-over is very frequent in a rather small segment such as the short arm of chromosome 13 and constant in the distal band of the long arm of chromosome 10.
π SIMILAR VOLUMES
A case of partial trisomy 9 is described in a mentally retarded and dysmorphic child, confirming that this chromosome unbalance results in a characteristic clinical entity. This trisomy arose through aberrant segregation of translocation chromosome during meiosis in the patient's mother, who is a ba
In papillary thyroid carcinomas, the genes for receptor-type tyrosine kinase, RET or TRKA, are sometimes rearranged, resulting in fusion of its tyrosine kinase domain to 5Π portions of several activating genes. In a papillary thyroid carcinoma, we identified a novel gene (ELKS), the 5Π portion of wh
## Abstract __RUNX1__ (previously __AML1__) is involved in multiple recurrent chromosomal rearrangements in hematological malignances. Recently, we identified a novel fusion between __RUNX1__ and __LPXN__ from an acute myeloid leukemia (AML) patient with t(11;21)(q12;q22). This translocation genera