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Studies of the cardiovascular effects of nociceptin and related peptides

✍ Scribed by Maria Bonaria Salis; Costanza Emanueli; Anna Franca Milia; Remo Guerrini; Paolo Madeddu

Book ID: 117407807
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 540 KB
Volume: 21
Category: Article
ISSN: 0196-9781
DOI: 10.1016/s0196-9781(00)00238-2

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## Abstract Nociceptin, a 17‐amino acid peptide (FGGFTGARKSARKLANQ, N/OFQ), is the endogenous ligand of the nociceptin/orphanin FQ (NOP) receptor. This receptor–ligand system is involved in various physiological as well as pathophysiological mechanisms, but owing to the peptidic structure, it is ra