Studies of the application of lysosome stabiliser to the treatment for liver disorders
β Scribed by Shiraishi, T. ;Matsushima, T. ;Tsunematsu, K. ;Maekawa, I. ;Suzuki, S.
- Publisher
- Springer-Verlag
- Year
- 1969
- Tongue
- English
- Weight
- 70 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0435-1339
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## Abstract Disorders that arise as a result of lysosomal dysfunction represent some of the most challenging diagnostic problems in medicine. Not only are these disorders infrequently seen, but they may also present with signs and symptoms that mimic perinatal injury, food intolerance, or the seque
Lysosomotropic agents are selectively taken up into lysosomes following their administration to man and animals [de Duve et al. (1974) Biochem. Pharmacol. 23:2494-2531] The effects of lysosomotropic drugs studied in vivo and in vitro can be used as models of lysosomal storage diseases. These agents