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Studies of substrate requirements, kinetic properties, and competive inhibitors of the enzymes catabolizing TRH in rat brain

✍ Scribed by W.H. Busby Jr.; W.W. Youngblood; J.S. Kizer


Book ID
118867521
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
820 KB
Volume
242
Category
Article
ISSN
0006-8993

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The effect of MnZ+, a divalent metal, on the enzyme K+-p-nitrophenyl phosphatase (K+-PNPPase) was studied in rat brain. The metal was found to be a moderate inhibitor of the enzyme, with an Is0 of approximately 4 8 0 ~~. The inhibition was pH dependent, but not temperature dependent. On measurement