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Studies of sterol synthesis, synthesis regulation and transport in cultured human kidney

โœ Scribed by GONZALEZ, R; DEMPSEY, M; ELLIOTT, A; FRALEY, E

Book ID
123041515
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
552 KB
Volume
87
Category
Article
ISSN
0014-4827

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Sterol synthesis in liver in vivo is regulated at the site of the reaction catalyzed by 3-hydroxy-3-methylglutaryl-CoA reductase through a feedback system thought to involve either cholesterol or one or more of the products of its metabolism. Cholesterol feeding results in repression of the synthesi