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Studies of ruthenium(II) polypyridyl complexes on cytotoxicity in vitro, apoptosis, DNA-binding and antioxidant activity

โœ Scribed by Hong-Liang Huang; Yun-Jun Liu; Cheng-Hui Zeng; Jun-Hua Yao; Zhen-Hua Liang; Zheng-Zheng Li; Fu-Hai Wu


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
872 KB
Volume
966
Category
Article
ISSN
0022-2860

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In an attempt to establish fundamental structure-activity relationships (SAR) of Pt/Pd-based anti-tumour compounds, we have recently designed monodentate pyridyl amide ligand containing central amide units which possess external metal co-ordinating pyridyl group and internal amide functionality. It