A novel synthesis of 3,4-disubstituted c
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Alexander S. Kiselyov; Celia Dominguez
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Article
📅
1999
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Elsevier Science
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French
⚖ 235 KB
An efficient synthesis of 3-aryl-4-aminocinnolines from ortho-trifluoromethylphenyl hydrazones is described. The mechanism of the described transformation is likely to involve the formation of the quinone methide intermediate. The described procedure is easily adaptable to automated solid phase syn