Studies of Imidazole Compounds. V. A New and Improved Synthesis of 4-(2-Substituted Aminoethyl)-imidazoles
β Scribed by Huebner, Charles F.
- Book ID
- 127022576
- Publisher
- American Chemical Society
- Year
- 1951
- Tongue
- English
- Weight
- 391 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
The electrophilic properties of the 4H-imidazoles 1 and their protonated derivatives 2 permit the introduction of nucleophilic building blocks, as illustrated by reactions of 1 with selected amines. Depending on the nature of the amine and the substituents R 1 on the heterocycle 1, single (3) or dou
We have synthesized 2-(thienyl-2)imidazole and its N-methyl derivative. The latter product was obtained by nitration, bromination, acylation, and formylation, occurring as a rule on the thiophene ring. A general method for methylating 2-R-imidazoles with methyl iodide KOH--dimethoxy ethane is propos