Studies of Angiotensin-II Conformations by Circular Dichroism
β Scribed by Serge Fermandjian; Jean-Louis Morgat; Pierre Fromageot
- Book ID
- 115112964
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- English
- Weight
- 595 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1432-1327
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Since the enantiomers of the N-methyl-D-aspartate (NMDA) receptors antagonist ketamine have different pharmacological profiles, CD and UV spectroscopy were applied for the study of conformer equilibrium and pH dependence in ketamine solutions. The assignment of the configurations and conformations w
C'onfiirmutionul ,fk cnrrgy culciilutions using an empirical potential ECEPP/3 (Empirical Confbrmutional Energj? Program ,for Peptides, Version 3) wcrp carried oiit on angiotensin II ('4II) of'srqiicwc A,spArg-Val-T,~r-Ile-Hi.s-Pro-Phe to,find [he slahle conformarions ofthe,fiee stat(> in tho iinhjd