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Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin

✍ Scribed by Alan Cowan; Xing Zu Zhu; Frank Porreca

Book ID
119073419
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
285 KB
Volume
5
Category
Article
ISSN
0143-4179

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Solution Conformation of [D-Pen2,D-Pen5]
Solution Conformation of [D-Pen2,D-Pen5]enkephalin in Water: A NMR and Molecular Dynamics Study
✍ Martin Gußmann; Rolf Borsdorf; Hans–JΓΆrg Hofmann πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 457 KB

The solution conformation of [D-Pen2, D-Pen5] enkephalin (DPDPE), a highly potent delta-selective opioid agonist, was examined by means of NMR, molecular mechanics and molecular dynamics methods. The structural information in the solvent water was obtained employing one- and two-dimensional methods