Studies in sesquiterpenes—XVI : Zerumbone, a monocyclic sesquiterpene ketone
✍ Scribed by Sukh Dev
- Book ID
- 103398908
- Publisher
- Elsevier Science
- Year
- 1960
- Tongue
- French
- Weight
- 820 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0040-4020
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## Abstract Zerumbone (ZER), present in subtropical ginger __Zingiber zerumbet__ Smith, possesses anti‐growth and anti‐inflammatory properties in several human cancer cell lines. ZER also down‐regulates the cyclooxygenase‐2 and inducible nitric oxide synthase expression __via__ modulation of nuclea
## Abstract We recently showed that zerumbone, a sesquiterpene found in subtropical ginger, suppresses colonic tumor marker formation in rats and induces apoptosis in colon cancer cell lines. In our present study, the anti‐tumor initiating and promoting activities of zerumbone in mouse skin were ev