Studies in macrolide synthesis: A novel cyclodimerisation approach to the synthesis of elaiophylin using a double Stille cross-coupling reaction

✍ Scribed by Ian Paterson; Jocelyn Man

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 254 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(96)02395-7

✦ Synopsis

The 16-membered macrodiolide 4, corresponding to the macrocyclic core of elaiophylin (1), was prepared via the copper-mediated cyclodimerisation of stannane 3.