Studies directed toward the synthesis of
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Yonghai Chai; Zonghong Mou; Matthias C. McIntosh
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Article
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2010
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Elsevier Science
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French
⚖ 427 KB
The fully substituted hydroisobenzofuran core of the massileunicellins containing eight contiguous stereocenters was prepared in 12 steps from (S)-(+)-carvone. Noteworthy elements of the synthesis include a one-step oxidative rearrangement/epoxidation, a novel stereoselective directed reduction of a