Studies directed toward the synthesis of viridenomycin. Route 1: assembly of three advanced intermediates
β Scribed by Albert W Kruger; A.I Meyers
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 68 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Three enantiomerically and geometrically pure building blocks representing fragments of the antifungal antibiotic viridenomycin have been prepared.
π SIMILAR VOLUMES
A second generation approach toward the synthesis of viridenomycin is described. Three key fragments of the molecule have been synthesized in stereochemically pure form. Initial studies toward the coupling of these fragments with the aim of assembling the macrocycle are detailed. Final efforts to re
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An efficfent enanboseieciwe route to the actahydronaphlhabne uaf preseni II) tetronollde (I), the stereochem~calty complex aglycone common to the telrocarcms, a novel group of anlilumor substances, IS described The sequence employs the mtramolecular D/e/s-Aider reaction to control the relatrve stere