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Studien in der Lumiflavin-Reihe VII. Zur Kenntnis der 4-Desoxyflavine und der Struktur von Flavin-Metallchelaten

✍ Scribed by P. Bamberg; P. Hemmerich; H. Erlenmeyer


Publisher
John Wiley and Sons
Year
1960
Tongue
German
Weight
626 KB
Volume
43
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

The general instability of desoxy‐isoalloxazines has been confirmed by studying the formation and decomposition of 4‐phenyl‐4‐desoxy‐isoalloxazines and ‐alloxazines. It has been shown, that the former (4‐desoxy‐flavins) may be synthesized in the semiquinonoid radical state. These radicals react with O~2~ or H~2~O~2~ with fission of the 4‐substituents to give the analogous 4‐oxo‐compounds by a hydroperoxide rearrangement. In view of this instability, the oxinate like structure of flavin metal chelates may be excluded.