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Strukturanalyse von Scillicyanosid-pentahydrat. 58. Mitteilung über Herzglykoside [1]

✍ Scribed by André Jaunin; Hans Peter Weber; Albert Von Wartburg

Publisher
John Wiley and Sons
Year
1973
Tongue
German
Weight
497 KB
Volume
56
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The crystal structure of the steroidal glycoside scillicyanosid‐pentahydrate has been determined by X‐ray analysis. The rings of the steroid backbone are A/B cis, B/C trans, and C/D cis fused, the six substituents are all in β‐position (5β‐~D~‐gluco‐pyranoside, 10β‐aldehyde, 13β‐methyl, 14β‐hydroxy, 16β‐acetoxy, and a 17β‐lactone ring). The crystal structure displays a complex system of hydrogen bonds between the five water molecules and the various oxygen functions in the steroidal glycoside. There are no __intra__molecular hydrogen bonds. 624 structural parameters were refined to an R‐value of 0.059 with 1907 significant structure factors.

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