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Structures of TMC-120A, B and C, novel isoquinoline alkaloids from Aspergillus ustus TC 1118

✍ Scribed by Jun Kohno; Hajime Hiramatsu; Maki Nishio; Masaaki Sakurai; Toru Okuda; Saburo Komatsubara


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
300 KB
Volume
55
Category
Article
ISSN
0040-4020

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✦ Synopsis


Three novel isoquinoline alkaloids, TMC-120A, B and C (1-3) have been isolated from a fermentation broth of Aspergillus ustus (Bain.) Thom& Church TC 1118, a fungus isolated from rhizosphere of grass. Their structures were determined through extensive spectroscopic analyses and chemical studies. TMC-120s (1-3) are found to be the first furo[3,2-h]isoquinoline-type alkaloids isolated from natural sources.


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