Structures of the Muraymycins, Novel Peptidoglycan Biosynthesis Inhibitors.
β Scribed by Leonard A. McDonald; Laurel R. Barbieri; Guy T. Carter; Eileen Lenoy; Jason Lotvin; Peter J. Petersen; Marshall M. Siegel; Guy Singh; R. Thomas Williamson
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Peptidoglycan synthesis begins in the cytoplasm with the condensation of UDP-N-acetyl glucosamine (UDP-GlcNAc) and phosphoenolpyruvate catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase. UDP-GlcNAc is also utilized as substrate for the glycosyltransferase MurG, a membrane-bound enzyme tha
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Structures and Biosynthesis of Aflastatins: Novel Inhibitors of Aflatoxin Production by Aspergillus parasiticus. -The structures of aflastatins A and B (I) are elucidated by NMR experiments and chemical degradation experiments. The biosynthesis of both compounds (I) is investigated using 13 C-label