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Structures of the Escherichia coli PutA Proline Dehydrogenase Domain in Complex with Competitive Inhibitors †,‡

✍ Scribed by Zhang, Min; White, Tommi A.; Schuermann, Jonathan P.; Baban, Berevan A.; Becker, Donald F.; Tanner, John J.


Book ID
127028777
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
530 KB
Volume
43
Category
Article
ISSN
0006-2960

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Probing a hydrogen bond pair and the FAD
✍ Berevan A. Baban; Madhavan P. Vinod; John J. Tanner; Donald F. Becker 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 840 KB

The PutA flavoprotein from Escherichia coli combines DNA-binding, proline dehydrogenase (PRODH), and D 1 -pyrroline-5-carboxylate dehydrogenase (P5CDH) activities onto a single polypeptide. Recently, an X-ray crystal structure of PutA residues 87 -612 was solved which identified a D370 -Y540 hydroge