Karinolide 1 is a structurally novel C20 quassinoid isolated from the French Guyanan Simaroubaceae, Simaba mZtifZara A.Juss. whose structure was established by X-ray diFfraction analysis. 6a-Senecioyloxychaparrin 1, the known 6cl-senecioloyxychaparrinone 3 and 9-methoxy-
Structures of simarinolide and guanepolide (x-ray analysis), new quassinoids from Simaba cf orinocensis
✍ Scribed by Judith Polonsky; Zoīa Varon; Thierry Prange; Claudine Pascard; Christian Moretti
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 282 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Simarinolide 4a and Guanepolide 5a are new quassinoids with a C25 basic skeleton -isolated from a member of the French Guyanan Simaroubaceae, Simaba cf orinocensis H.B.K. The structure 4a was established by spectral means and that of 5a by X-ray diffraction --
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The results of X-ray diffraction analyses on two m-aminoisobutyric acid (Aibl derivativcs, methyl u-(acetylamino)isobuknoate (Ac-Aib-OMc. I ) and bcnzyl a-[(beazyloxycarbonyl)arnino]isobutanoate (2-Aib-OBA, 2), and two terminally blocked, Aib-conlining dipcptides, methyl cr-[(acctyl-~-alanyl)nmino]i