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Structures of N2-acetyl-dl-alaninamide and N2-acetyl-dl-leucinamide

โœ Scribed by Puliti, R. ;Mattia, C. A. ;Barone, G. ;Giancola, C.


Book ID
114508241
Publisher
International Union of Crystallography
Year
1991
Tongue
English
Weight
575 KB
Volume
47
Category
Article
ISSN
0108-2701

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N-Acetyl-DL-penicillamine (IIIb), a structural analog of N-acetyl-L-cysteine (IIIa), did not protect mice from lethal doses of acetaminophen (I), whereas IIIa offered protection. This lack of efficacy of IIIb probably is due to the decreased nucleophilicity of its sulfhydryl group compared to that o