Structured Nucleic Acid Probes for Electrochemical Devices
✍ Scribed by Rebeca Miranda-Castro; Noemí de-los-Santos-Álvarez; María Jesús Lobo-Castañón; Arturo J. Miranda-Ordieres; Paulino Tuñón-Blanco
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 465 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1040-0397
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## Abstract Chitosan, a naturally occurring biopolymer, was used as a scaffold for the covalent binding of single‐stranded DNA oligonucleotide probes in a fluorescence‐based nucleic acid hybridization assay. Chitosan's pH dependent chemical and electrostatic properties enable its deposition on elec