✦ LIBER ✦

Structure–Activity Studies of Phosphopeptidomimetic Prodrugs Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3 (Stat3)

✍ Scribed by Pijus K. Mandal, Zhiyong Ren, Xiaomin Chen…

Book ID: 120745919
Publisher: Springer Netherlands
Year: 2012
Tongue: English
Weight: 528 KB
Volume: 19
Category: Article
ISSN: 1573-3149
DOI: 10.1007/s10989-012-9313-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Investigation of the Binding Determinant

Investigation of the Binding Determinants of Phosphopeptides Targeted to the Src Homology 2 Domain of the Signal Transducer and Activator of Transcription 3. Development of a High-Affinity Peptide Inhibitor

✍ Coleman, ; Ren, Zhiyong; Mandal, Pijus K.; Cameron, Arlin G.; Dyer, Garrett A.; 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 343 KB

422 Targeting the SH2 domain of Stat3 wi

422 Targeting the SH2 domain of Stat3 with phosphopeptide mimetic prodrugs leads to tumor growth inhibition and down-regulation of phosphoTyr705 Stat3 and angiogenic pathways

✍ J. McMurray; J. Klostergaard; E.J. Auzenne; W.S.L. Liao; Z. Lu; P.K. Mandal; R. 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 64 KB

P-244 Distinct epigenetic modulation of

P-244 Distinct epigenetic modulation of signal transducer and activator of transcription (STAT) signaling in FOXP3+ T regulatory cells of CMML-2 patients

✍ Lamprianidou, E.; Miltiades, P.; Vassilakopoulos, T.P.; Papageorgiou, S.; Galano 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 72 KB

Phosphorylation of signal transducer and

Phosphorylation of signal transducer and activator of transcription 3 (STAT3) correlates with Her-2 status, carbonic anhydrase 9 expression and prognosis in esophageal cancer

✍ Schoppmann, Sebastian F.; Jesch, Bettina; Friedrich, Julia; Jomrich, Gerd; Maros 📂 Article 📅 2012 🏛 Springer 🌐 English ⚖ 447 KB

WITHDRAWN: Intrinsic molecular character

WITHDRAWN: Intrinsic molecular characteristics of inhibiting STAT3 activation and dimerization through targeting the phosphotyrosine binding site within the SH2 domain—A molecular dynamics study

✍ Fan, Yubo; Kong, Ren; Tweardy, David J.; Wong, Stephen T. 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 24 KB

REPLICATION PROTEIN A 32 kDa SUBUNI

REPLICATION PROTEIN A 32 kDa SUBUNIT (RPA p32) BINDS THE SH2 DOMAIN OF STAT3 AND REGULATES ITS TRANSCRIPTIONAL ACTIVITY

✍ Jeonghoon Kim; Dohoon Kim; Jongkyeong Chung 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 384 KB

## Abstract STATs (signal transducers and activators of transcription) are transcription factors that contain SH2 domains and are activated by tyrosine phosphorylation in response to cytokines and growth factors. Replication protein A (RPA) is a heterotrimeric complex that consists of three subunit