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Structure−Activity Studies of l -Canaline-Mediated Inhibition of Porcine Alanine Aminotransferase

✍ Scribed by Worthen, David R.; Ratliff, Darian K.; Rosenthal, Gerald A.; Trifonov, L.; Crooks, Peter A.


Book ID
121450594
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
362 KB
Volume
9
Category
Article
ISSN
0893-228X

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✍ Supinan R. Na Phuket; Latchezar S. Trifonov; Chongxi Yu; David R. Worthen; Peter 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 2 views

A number of congeners of the antitumor compound L-canaline, [L-2-amino-4-(aminooxy)butyric acid], a structural analog of L-ornithine, have been synthesized and their growth-inhibitory effects evaluated in cultured MIA-PaCa-2 cells, a human pancreatic adenosarcoma, by the 3-(4,5-dimethylthiazol-2-yl)