Structure—Activity Relationships in Environmental Sciences

✍ Scribed by Monika Nendza (auth.)

• Publisher: Springer US
• Year: 1998
• Tongue: English
• Leaves: 278
• Edition: 1
• Category: Library

✦ Synopsis

Structure-Activity Relationships in Environmental Science is the first book of its kind that brings together information from a variety of sources into one document. It provides a comprehensive overview of the entire field of quantitative structure-activity relationships (QSARs) as well as being a reference for SAR experts.
The book comprises three parts. Part One covers the theoretical background of structure-activity studies and Part Two deals with the practical applications of such methods in the environmental sciences. Part Three critically discusses SAR models with respect to their reliability and their aptness in environmental hazard and risk assessment. Recommendations are made as to which model to use and the case is presented for using QSARs in hazard assessment.
The use of QSARs is becoming increasingly important since there is little experimental data available on environmentally relevant chemicals. Structure-Activity Relationships in Environmental Sciences will thus serve as an invaluable guide to both postgraduate and research scientists as well as professional ecologists.

✦ Table of Contents

Front Matter....Pages i-xiv
Introduction....Pages 1-10
Front Matter....Pages 11-14
Descriptors of the chemical structures....Pages 15-46
Activity and effects parameters....Pages 47-61
Statistical methods....Pages 63-88
Front Matter....Pages 89-90
Exposure-related parameters....Pages 91-141
Effects-related parameters....Pages 143-188
Validation status of QSAR models for exposure- and effects-related parameters....Pages 189-192
Front Matter....Pages 193-193
Assessments of chemical mixtures....Pages 195-199
Interspecies correlations....Pages 201-206
Application of QSAR estimates in hazard evaluation and risk assessments....Pages 207-224
Back Matter....Pages 225-269

✦ Subjects

Ecotoxicology; Physical Chemistry