𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structure–activity relationships for the mutagenicity and carcinogenicity of simple and α-β unsaturated aldehydes

✍ Scribed by Romualdo Benigni; Laura Passerini; Andrea Rodomonte


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
108 KB
Volume
42
Category
Article
ISSN
0893-6692

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Simple and α,β-unsaturated aldehydes: Co
✍ Romualdo Benigni; Luigi Conti; Riccardo Crebelli; Andrea Rodomonte; Maria Rosari 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

Aldehydes are widespread environmental and industrial compounds, able to stimulate a range of adverse health effects (e.g., general toxicity, allergenic reactions, mutagenicity, and carcinogenicity). We have previously presented quantitative structure-activity relationships (QSARs) for the genotoxic

Structure–activity relationships for hep
✍ Katie Chan; Peter J. O'Brien 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB

## Abstract Covalent binding of reactive electrophiles to cellular targets is a molecular interaction that has the potential to initiate severe adverse biological effects. Therefore, electrophile reactivity towards biological nucleophiles could serve as an important correlate for toxic effects such

Application of structure–activity relati
✍ Katie Chan; Raymond Poon; Peter J. O'Brien 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 405 KB

## Abstract Covalent binding of reactive electrophiles to cellular targets is a molecular interaction that has the potential to initiate severe adverse biological effects. Therefore, a measure for electrophilic reactivity with biological nucleophiles could serve as an important correlate to toxic e

Comments on the Mutagenicity of α,β-Unsa
✍ Errol Zeiger 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB

In a recent article in Environmental Mutagenesis [9:289-295, 19871, "Mutagenicity and Toxicity Studies of Several a$-Unsaturated Aldehydes in the Salmonella typhimurium Mutagenicity Assay," K.O. Cooper et al provided support for a phenomenon that had been described earlier by Ames et al [1975], Maro